Genervon holds 82 issued U.S. and international patents
The inventions include composition of matter patents which are directed to novel peptides and compositions capable of modulating viability and growth in neuronal cells and to methods of modulating neuronal cell viability and growth employing the novel peptides and compositions of the invention.
The patents include methods for treating neuronal disorders and diseases using motoneuronotrophic factor (MNTF) or its peptide analogs.
The inventions also include methods for inducing differentiation of an embryonic stem cell into a motor neuron using a motoneurontrophic factor (MNTF) or its peptide analogs. The patents further provides a method of enhancing the survival of the differentiated neural cells in long term cell cultures and provide compositions containing MNTF or its peptide analogs for therapeutic use in conjunction with stem cells.